Coding
IbpB

Part:BBa_K1620003

Designed by: Celio Dias Santos Jr   Group: iGEM15_UFSCar-Brasil   (2015-09-03)

small heat shock protein IbpB

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Usage and Biology

IbpB is a small heat shock protein. It is expressed under stress conditions which associate with aggregated proteins. It acts together with IbpA to stabilize and protect aggregated proteins from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent. It is extensively documented in the following link: http://www.uniprot.org/uniprot/P0C058. In our project, we have figured out to construct a protein solubilization device for high rate expressed proteins.

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Categories
//cds
Parameters
None